Post a New Topic
Original post made
on Jun 5, 2008
This is really scary news. Thank you The Danville Weekly forproviding the information on how to protect yourself.
My biotech company has had encouraging results treating West Nile virus encephalitis since 2003: 81% treatment success rate in people (22 of 27), 75% in horses (6 of 8), and 50% in birds (6 of 12).
Our approach works best when people first have symptoms of a fever and headache. But we've been able to help people even a few years after the initial episode of WNV encephalitis.
Our first 8 WNV patients were published in a peer-reviewed medical journal in 2004 (1). We're eager to see if our approach works again this year.
The drugs we use are already approved by the FDA for blood pressure. They seem to be anti-inflammatory, too. People with a normal immune system who get sick from the West Nile virus appear to overdo their immune response to the virus. Our approach is meant to gently calm down their exaggerated immune response, the so-called "cytokine storm." It can be used in the very old, the very young, and everybody in between.
It can also be used for almost any virus except the herpes viruses, which is why our approach was included in the BioShield II Act of April 28, 2005, co-sponsored by Senators Lieberman, Hatch, and Brownback. The bill was never debated, but our approach was mentioned in Section 2151 (Web Link). In 2004, I briefed the White House and the Dept of Homeland Security about it. The UN is aware of our approach in the context of bird flu, although they haven't tested it, preferring to push Roche's drug Tamiflu instead.
Although our approach looks quite useful, the CDC no longer even talks to us. State public health authorities, taking their cue from the CDC, tell reporters that they've never heard of us, or that we're making up our data. This isn't the least bit helpful. If they don't believe our data, they should at least put our method to the test. As fellow professionals, they owe us that much. Pontification without experimentation is the opposite of the scientific method.
Public health authorities used to run clinical trials. Now they merely test blood samples. In effect, the CDC has become like the Hanes lady. Nobody dies of WNV unless the CDC says they did. The CDC's total lack of interest in testing a promising treatment boggles the mind.
The CDC reminds me a lot of FEMA.
On the other hand, this vacuum in public health represents an enormous business opportunity, akin to IBM's sticking to hardware and leaving software to people like Bill Gates.
The drugs we use cost about $1 a tablet. We use one or two pills a day. They're carried in every drugstore on earth. We don't sell the tablets, we just sell the license to use them. But we have no great illusions that we'll be able to collect license fees for such short-term use. Frankly, this is a loss-leader for us, equivalent to AOL's handing out free Internet hours.
But if our treatment works, it will be a sweet deal for public health, which is GenoMed's main concern.
Anybody who wants to download our WNV trial protocol can do so for free at any time by clicking on the "West Nile trial" link on our company's homepage at www.genomed.com.
Incidentally, contrary to popular belief, the people who get sick from West Nile have unusually strong immune systems, not "weakened" ones. Only if you're taking chemotherapy or Prednisone is your immune system weak. Otherwise, you should hope for no cytokine storm with WNV, I believe.
1: Moskowitz DW, Johnson FE. The central role of angiotensin I-converting enzyme in vertebrate pathophysiology. Curr Top Med Chem. 2004;4(13):1433-54. PMID: 15379656 (For PDF file, click on paper #6 at: Web Link) -- see Table 2 for WNV patients
Dave Moskowitz MD FACP
CEO, GenoMed, Inc.
"The public health company™"
Ticker symbol: GMED (on the Pink Sheets)
thanks for the tips on how to not get bit by a mosquito.
I met a woman in a wheelchair in an airport who said she was partially paralyzed after she had West Nile virus. She was from soemwhere backeast.
Don't miss out on the discussion!
Sign up to be notified of new comments on this topic.
Post a comment
Posting an item on Town Square is simple and requires no registration. Just complete this form and hit "submit" and your topic will appear online.
Please be respectful and truthful in your postings so Town Square will continue to be a thoughtful gathering place for sharing community information
We prefer that you use your real name, but you may use any "member" name you wish.
Select your neighborhood or school community: *
- San Ramon
- Walnut Creek
- Alamo Elementary School
- Charlotte Wood Middle School
- Del Amigo Continuation High School
- Diablo Vista Middle School
- Green Valley Elementary School
- Greenbrook Elementary School
- John Baldwin Elementary School
- Los Cerros Middle School
- Montair Elementary School
- Monte Vista High School
- Rancho Romero Elementary School
- San Ramon Valley High School
- Stone Valley Middle School
- Sycamore Valley Elementary School
- Tassajara Hills Elementary School
- Venture Independent Study School
- Vista Grande Elementary School
- another community
Verification code: *
Enter the verification code exactly as shown, using capital and lowercase letters, in the multi-colored box.
The Heart of the Constitution
By Tom Cushing | 5 comments | 369 views
Bidding my Maverick Bye-Bye
By Roz Rogoff | 3 comments | 225 views
Home & Real Estate
Send News Tips
© 2015 DanvilleSanRamon.com
All rights reserved.