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Solving a big problem in the basement on 2nd Street in Livermore

Uploaded: Jul 30, 2020
Three years ago Tom Olenic and George Farquar set out to use cutting-edge technology to solve a vexing problem for employers and law enforcement -- how to efficiently determine whether a person was impaired from marijuana.

Olenic is a serial life entrepreneur while Farquar spent 10 years working at Lawrence Livermore National Laboratory on chemical analysis before joining Olenic as a serial entrepreneur. Since leaving the lab, he's been part of four different start-ups with Buzzkill Labs in Livermore being the latest.

With recreational marijuana now legal in 11 states and medical marijuana legal in 33, it's a big problem. Unlike alcohol that is water-soluble so breath, urine and blood tests are all reliable, the active ingredient in marijuana, THC, is fat-soluble. Urine tests can determine past use, but cannot determine current impairment.

For law enforcement pursuing an impairment case, that means getting a warrant after the arrest, bringing in a person to draw blood and then awaiting the test results. It's very expensive. Officials have designed a field test specifically for the mental impairment caused by THC that can provide probable cause for an arrest. .

In their discussion with police departments, the immediate question becomes when can they get a unit? Current testing programs can determine if a person has used THC, but cannot quantify the degree of impairment.

Think about a person driving a bus or heavy equipment or a construction worker on a ladder or a high-rise building. It's legal for them to have smoked a joint after work or eaten a marijuana edible the night before. The edibles can be particularly challenging because a person smoking the traditional joint will get high quickly when the THC is absorbed into the blood stream through the lungs. It can take 30 minutes or more for the THC to work is way through the digestive system -- a delay that can invite a second helping.

The Buzzkill solution is tests using a simple saliva swab. Farquar already has proved the concept based on a series of tubes and plungers, and they've now developed their first prototype that they are refining. The next step is to bring it to market on a pilot basis early next year.

They're poured all of their time and money into developing the machine that will be completely automated once the swab sample is inserted. They've outsourced the engineering to the same company that serves 10X Genomics and its life science analytic tools.

They've been working in the basement of the incubator Daybreak Labs on Second Street in downtown Livermore. As a true startup, they painted their space themselves as well as hanging a drop ceiling. If you've lived here long enough, you will recognize it as the former JCPenney store in the pre-Stoneridge Mall days or, more recently, the ValleyCare Thrift Store.

When the pandemic hit and the incubator shutdown, Farquar set up a lab in his garage. He was doing double-duty because his first-grade daughter was home. His wife works for Lawrence Livermore so he was dad, teacher and researcher. Their chief chemist was working in his kitchen and then riding his bike across Livermore to deliver the samples to Farquar for processing.

Their machine is designed to deliver results in less than 15 minutes after the saliva sample is collected. It weighs less than 20 pounds and will operate by pushing one button. In addition, it will have the capability to test a variety of drugs: THC, morphine, hydrocodone, oxycodone, 6- acetylmorphine, phencyclidine, amphetamine/methamphetamine, to name a few.

Statistics from 2018 indicate that 43.5 million Americans used marijuana that year or about 16% of the population. About 27.7 million used it in the past month.

Their goal is to produce a finished product for around $20,000 that they can rent to agencies based upon the number of tests they conduct. Each test requires a disposable sample that potentially becomes the cash flow for Buzzkill. It's why the razor companies will give you the razor so they can sell you the blades -- same concept.

The company started with $1.2 million in seed funding and Olenic now is starting to raise the next round from venture capitalists in the $3 million to $3.5 million range. This will allow Buzzkill to start to scale and develop the sales and marketing teams as well as ramp up manufacturing.

They believe the market and opportunity is huge as marijuana continues to be legalized and employers become increasingly concerned about testing potential impaired workers. Worldwide, Buzzkill's white paper, estimates that the drug screening market was $7.1 billion in 2019 and is expected to double by 2027. Positive tests for marijuana increased significantly from 2015-18

These trends effect worker productivity, on-the-job injuries and workers comp claims as well as additional health problems driving up insurance rates. The Buzzkill founders believe they have developed the right technology to address this big problem. Despite the COVID-19 remote working, they plan to hit the market next year.

Community.
What is it worth to you?

Comments

Posted by Cholo, a resident of Livermore,
on Jul 30, 2020 at 9:59 am

well...if merry-anna is sinful I don't know what...at my age, I don't care what anybody thinks about what I enjoy!

I know lots of folks who indulge from time to time, we're all thriving, giggling, and loving the apple pie that I bake.

I can hardly believe that in 2020 anybody is worried about brownies laced with stuff...duh


Posted by Cholo, a resident of Livermore,
on Jul 30, 2020 at 10:01 am

i rest my case...


Posted by Jo, a resident of Parkside,
on Jul 30, 2020 at 10:37 am

Jo is a registered user.

you missing the main point cholo "impairment" as in operating a vehicle as the prime example. I think we can all agree we dont want "high" people driving cars around. If they just want to stay home and eat your apple pie, I have no issues.


Posted by Cholo, a resident of Livermore,
on Jul 30, 2020 at 11:59 am

oh my...I forgot...i don't drive...


Posted by Cholo, a resident of Livermore,
on Jul 30, 2020 at 12:06 pm

Plutonians love to drink and get waaaaaay drunks!

Web Link


Posted by Kevin, a resident of Castlewood,
on Jul 30, 2020 at 12:52 pm

Kevin is a registered user.

I recommend the Netflix documentary Business of Drugs. For marijuana, according to the show, the Vey high financial and regulatory barriers to entering legal marijuana business is forcing big illegal black markets and increase use of cheap synthetic pot which is extremely dangerous.

The documentary highlights other types of drugs including fentanyl, heroin and MDMA (ecstasy). A UC Berkeley chemist living in Lafayette formulated MDMA for PTSD and therapies for mental diseases. Once Reagan signed law against all types of drugs, scientists could no longer study MDMA. Things are changing slowly and clinical studies have been done that show MDMA helps soldiers with PTSD.

Bottom line - it seems that our government approach to drugs has proven Ineffective and has made things worse. FDA approved Fentanyl and let Pharma companies entice doctors to prescribe it excessively which resulted in Addictionsand deaths of thousands of people.


Posted by Jo, a resident of Parkside,
on Jul 30, 2020 at 9:40 pm

Jo is a registered user.

Cholo: ok but lets taste that apple pie then


Posted by [email protected], a resident of another community,
on Jul 31, 2020 at 8:52 am

[email protected] is a registered user.

Very interesting article. Thanks for sharing informative posts like this.

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Posted by Cholo, a resident of Livermore,
on Jul 31, 2020 at 8:59 am

Jen...you sure know how to tease a person!


Posted by [email protected], a resident of California Reflections,
on Jul 31, 2020 at 9:15 am

[email protected] is a registered user.

Cool post! I hope meet you soon.


Posted by Kjgamble, a resident of San Ramon,
on Jul 31, 2020 at 10:04 am

Kjgamble is a registered user.

Hmmmmm. I don't see cannabis as a true impairment, no more than a spoon of cough syrup. Should we test for that as well? What about prescriptions? Do people drive after taking a pain pill, mood relaxer or anxiety pill? Should we test for those? Resources for this project could be best allocated elsewhere.


Posted by Kjgamble, a resident of San Ramon,
on Jul 31, 2020 at 10:05 am

Kjgamble is a registered user.

Hmmmmm. I don't see cannabis as a true impairment, no more than a spoon of cough syrup. Should we test for that as well? What about prescriptions? Do people drive after taking a pain pill, mood relaxer or anxiety pill? Should we test for those? Resources for this project could be best allocated elsewhere.


Posted by Michael Milburn, a resident of another community,
on Jul 31, 2020 at 11:01 am

This saliva test does not measure impairment, just use. It ignores the scientifically demonstrated fact that frequent cannabis consumers (e.g., medical cannabis patients) can develop tolerance to the psycho-active effects of cannabis.
No one should drive impaired, but actual impairment should be measured. We need a paradigm shift in our thinking about impairment testing. Please see: Web Link

We (Impairment Science, Inc.) have developed a new public health app that is an objective measure of impairment from cannabis or any source--anything that impairs reaction time, hand-eye coordination, balance and the ability to perform divided attention tasks--it is called DRUID (an acronym for “DRiving Under the Influence of Drugs") available now in the App Store and Google Play. DRUID statistically integrates hundreds of data points into an overall impairment score and takes just 2 minutes. The first peer-reviewed journal article validating DRUID is here (Web Link See www.druidapp.com


Posted by [email protected], a resident of another community,
on Aug 3, 2020 at 12:45 am

[email protected] is a registered user.

Thank you for this informative post. I hope to read more valuable articles like this here. Web Link


Posted by Ronald M. Lynch, a resident of Carlton Oaks,
on Aug 3, 2020 at 8:09 am

Ronald M. Lynch is a registered user.

Pretty good post. I just stumbled upon your blog and wanted to say that I have really enjoyed reading your blog posts. Any way I'll be subscribing to your feed and I hope you post again soon. Web Link


Posted by lomixgropijdih, a resident of Valley View Elementary School,
on Aug 6, 2020 at 3:59 am

lomixgropijdih is a registered user.

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